Back to 4.3: Debulking
The trick to this crossword is that some of the answers need to cross into the black zones! Examples include 7 Down, the starting numbe of which isn't even marked as it's located in the black zone.

The letters in the black zones (ordered by row) spell CRYOSURGERY.
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Guess log
Frequency | Guess |
---|---|
19 | CRYOSURGERY |
8 | CRYOTHERAPY |
2 | CYTOGENETIC |
2 | CYTOGENETICS |
2 | CYTOMETRY |
2 | CYTOREDUCTION |
1 | CRYFORHELP |
1 | CRYOMETERY |
1 | CRYOPROTEIN |
1 | CRYOREDUCTION |
1 | CYTOGENESIS |
1 | CYTOMETRIC |
1 | CYTOPLASM |
1 | CYTOREDUCTIVE |
1 | CYTOREDUCTIVESURGERY |
1 | CYTOREDUCTIVETHERAPY |
1 | CYTOTHERAPY |
1 | CYTOTOXIC |
1 | CYTOTOXICITY |
1 | EPIDEMIOLOGY |
1 | FATHEROFEPIDIMEOLOGY |
1 | JOHN |
1 | JOHNSNOW |
1 | JONSNOW |
1 | MICROSPHERE |
1 | RADIOSURGERY |
1 | SNOW |