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Pathway 4, Subject 3

Debulking

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You will need some additional letters to complete this crossword — read these letters from top-to-bottom and left-to-right to reach this puzzle's thematic answer.

The surgical procedure has removed quite a few walled-off tumours... However, it seems to have left some deletions and mutations behind...

Across
  1. One of the tests that a lymph node biopsy is often sent off for
  2. eviQ is an example of this, herbal remedies for cancer are not (acronym)
  3. Sample
  4. Deterrent for most people to access CAR T-cell therapy or bispecific antibody therapy in the United States
  5. Common rheumatological differential for 34a (acronym)
  6. Can represent a component of differentiation syndrome in the treatment of acute promyelocytic leukaemia
  7. What a patient might be left with following 40a
  8. C-reactive protein and albumin are respective examples of positive and negative versions of these that occur in the acute phase of inflammation
  9. How a patient with colorectal cancer might present (acronym)
  10. Critical and time-sensitive, as in starting patients on cancer treatment
  11. Refers to therapy given after surgery to eliminate any remaining cancer cells and prevent recurrence
  12. Scar-like (from Greek)
  13. Surgical team that might manage a cholangiocarcinoma (acronym)
  14. Gold-standard imaging modality that assists doctors with diagnosing, staging, and monitoring cancer (acronym)
  15. How a patient with malignancy might present (acronym)
  16. Bone that may be affected by local spread of thyroid cancer
  17. Particle emitted by fluorodeoxyglucose
  18. Most important risk factor for cancer
  19. Definitive treatment of localised colon cancer
  20. Common and harmless differential for sebaceous carcinoma
Down
  1. What may follow Burkitt or Hodgkin
  2. Online presentation — for example, how teaching on cancer might be delivered
  3. Common complication when chemotherapy is initiated, particularly in cases with large burden of malignancy (acronym)
  4. Malignancy of plasma cells
  5. Very rare genetic syndrome that affects the skin and increases the risk of developing basal cell carcinoma
  6. Period between initial cancer treatment and relapse
  7. Common minimally invasive procedure used to diagnose thyroid cancers (acronym)
  8. A tumour marker that is used to monitor prostate cancers (acronym)
  9. A tumour marker that is elevated in colorectal cancers, as well as lung, breast, and ovarian cancers (acronym)
  10. Common haematological tests are collected in this kind of tube
  11. Essential thrombocythaemia leads to a high value for this laboratory test (acronym)
  12. Chemotherapy could be considered as this for cancer
  13. Virus linked to increased risk of developing acute lymphoblastic leukaemia (acronym)
  14. Metastatic
  15. A tumour marker that is elevated in hepatocellular carcinoma and germ cell tumours (acronym)
  16. Type of stent that may be deployed to relieve malignant ureteric obstruction
  17. Hormone that small cell lung cancers might secrete as part of a paraneoplastic syndrome (acronym)
  18. Masses or lesions
  19. One of the tests that a lymph node biopsy is often sent off for (abbrev.)
  20. Training pathway that all budding oncologists and haematologists must embark upon (acronym)
  21. This is sampled in a faecal occult blood test
  22. A non-malignant differential of prostate cancer (acronym)
  23. This type of acid is released in tumour lysis
  24. This prefix, combined with 25a, refers to therapy given before surgery to shrink the tumour