Act II, Scene 1
Cher Aids
Hint
The title refers to "charades", and each clue refers to a rare disease. Is there an authoritative online list of such diseases? As an example, the first clue is charades for a genetic disease where p53 is mutated. Once you're done, take the first letters to get the cluephrase.
These rare clues sure sound sick!
Thumb war lots! (2-8)
Put a question to an insignificant member of the system (7)
Nystagmus drink (6)
Shock, Braff and Galifianakis (3-5)
Devour alcohol (7)
Skateboard trick hang time (6)
Sandwiches fork tip Swift-winged insect (10-5)
Propel straw (6)
Disgust footballer Walcott's sibling (10)
Recognised grandma... (6)
...and she made out Do (5-5)
Leer at peace sign (7)
Batman's partner currently (7)
Party, bender, bath! (5-7)
Every harbour (6)
Tunnel Beatle holes (7-5)
Make beer Irish police (7)
Steal window base green in French (7-6)
Mistook 10c coin - fool! (7-7)
Conceal low haemoglobin (9)